|
KMID : 0604520200460020159
|
|
Journal of the Society of Cosmetic Scientists of Korea
2020 Volume.46 No. 2 p.159 ~ p.166
|
|
|
Comparative Study of the Biological Activity of Propolis Extracts with Various Countries of Origin as Cosmetic Materials
|
|
Jung Eun-Sun
Weon Jin-Bae
Ji Hyang-Gi
You Ji-Young
Oh Se-Young
Kim Ha-Yeon
Xin Yingji
Kim Eun-Bin
Heo Kang-Hyuck
Park Deok-Hoon
|
|
|
Abstract
|
|
|
|
Propolis is a sticky resinous substance that is formed by the combination of honeybee secretions and resin of plants, which serves to protect from bacteria and viruses. This study aims to evaluate the efficacy of propolis extract from Korea (KPE), China (CPE), and Brazil (BPE) through antioxidant, antibacterial, whitening, and anti-inflammatory tests, and to examine their potential as cosmetic materials. KPE, CPE, and BPE showed significant antioxidant activities on flavonoid/polyphenol content and free radical scavenging activity. The antibacterial effect of propolis on skin flora was determined by measuring the minimal inhibitory concentration (MIC). KPE showed better antibacterial efficacy than CPE and BPE in C. acnes (KPE, CPE, and BPE: (62.5, 250, and 500) μg/mL, respectively). Furthermore, KPE inhibited the melanin synthesis in human epidermal melanocytes and production of nitric oxide and PGE2 induced by lipopolysaccharide (LPS) in mouse macrophages, which showed better than did CPE or BPE. Taken together, the propolis extracts can be applied to antioxidant, antibacterial, and anti-inflammatory ingredient for cosmetics, while KPE showed superior potential in antibacterial, anti-inflammatory, and whitening efficacies.
|
|
|
KEYWORD
|
|
|
Propolis, Antioxidant, Antibacterial, Anti-inflammation, Melanin synthesis
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|